Aqueous reductive amination using a dendritic metal catalyst in a dialysis bag

• Jorgen S. Willemsen,
• Jan C. M. van Hest and
• Floris P. J. T. Rutjes

Beilstein J. Org. Chem. 2013, 9, 960–965, doi:10.3762/bjoc.9.110

• metal complex to DAB-Am dendrimers via an adapted asymmetric bipyridine ligand. These dendritic catalysts were applied in the aqueous reductive amination of valine while contained in a dialysis bag. Comparable conversions were observed as for the noncompartmentalized counterparts, albeit with somewhat

• longer reaction times. These results clearly show that the encapsulated catalyst system is suitable to successfully drive a complex reaction mixture with various equilibrium reactions to completion. Keywords: aqueous reductive amination; cascade catalysis; compartmentalization; dendritic catalysts

• ]. Dendrimers can also be used as scaffolds for creating macromolecular catalysts [19], which generally show only a limited loss in activity compared to their “nonexpanded” congeners [20][21]. Such dendritic catalysts are kept in a compartment due to the macromolecular nature of these polymers, and have been

Olefin metathesis in nano-sized systems

• Didier Astruc,
• Abdou K. Diallo,
• Sylvain Gatard,
• Liyuan Liang,
• Cátia Ornelas,
• Victor Martinez,
• Denise Méry and
• Jaime Ruiz

Beilstein J. Org. Chem. 2011, 7, 94–103, doi:10.3762/bjoc.7.13

• steric congestion is also responsible for the decrease of the catalytic activity of Ru and Pd high-generation dendritic catalysts, even when these metallodendritic catalysts are soluble. The X-ray crystal structure of the model mononuclear complex in which the dendritic branch was replaced by a benzyl